Endocrine Abstracts

Background: Polycystic ovary syndrome (PCOS) is a highly prevalent heterogeneous disease associated with ovulatory dysfunction and hyperandrogenemia. Recent data support a critical role of neuroendocrine dysfunction and metabolic disturbances in the pathophysiology of the syndrome, including hyperleptinaemia. Accumulating evidence suggests that circadian desynchrony is linked to obesity and metabolic syndrome (MetS). Both prevalence and incidence of the metabolic syndrome is v...